Optimising rigid motion compensation for small animal brain PET imaging
نویسندگان
چکیده
منابع مشابه
Small animal PET imaging.
Positron emission tomography (PET) is well established as an important research and clinical molecular imaging modality. Although the size differences between humans and rodents create formidable challenges for the application of PET imaging in small animals, advances in technology over the past several years have enabled the translation of this imaging modality to preclinical applications. In ...
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PurposeInter-frame and intra-frame motion can adversely impact the performance of dynamic brain PET imaging. Only correcting the former can still result in degraded qualitative and quantitative performance. Meanwhile, patient motion introduces mismatches between transmission and emission data which may lead to incorrect attenuation and scatter compensation in the reconstruction process. As a re...
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UNLABELLED The purpose of this study was to investigate whether a correction for annihilation photon attenuation in small objects such as mice is necessary. The attenuation recovery for specific organs and subcutaneous tumors was investigated. A comparison between different attenuation correction methods was performed. METHODS Ten NMRI nude mice with subcutaneous implantation of human breast ...
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Increasingly, in vivo imaging of small laboratory animals has become critical for preclinical biomedical research allowing the non-invasive assessment of biological and biochemical processes in living subjects. Many di erent positron labeled compounds have been synthesized as tracer that target a range of speci c markers or pathways yielding quantitative, spatially and temporally indexed inform...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2016
ISSN: 0031-9155,1361-6560
DOI: 10.1088/0031-9155/61/19/7074